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Arthropods: venoms and biology

Guest editors: Luis Fernando García Hernández, Maria Elena de Lima and Wilson Lourenço
Arthropods: venoms and biology


Call for papers in the Journal of Venomous Animals and Toxins including Tropical Diseases


Edited by: Luis Fernando García Hernández, Maria Elena de Lima and Wilson Lourenço


Arthropods represent the most diverse animal phylum. The group not only exhibits an enormous diversity, but also a fascinating array of strategies for defense and prey capture. Many, if not most, arthropods possess behavioral and morphological adaptations to avoid predation or enhance the capture of their prey. Nevertheless, one of the most interesting and diverse strategies observed in many arthropods for defensive and feeding purposes is the use of toxic substances.

Many arthropod groups such as insects, arachnids and centipedes use venom for paralyzing or subduing their prey. The use of toxins may protect the predator from possible prey retaliation and in some cases promotes prey digestion. In many cases predation is closely associated with a given type of prey, consequently, specialized toxins can be observed. In account of new techniques that can evaluate animal toxicity, new studies can now explore potential associations between arthropod toxicity and type of prey.

Arthropods equally use toxic compounds in defensive strategies, to deter attack from potential predators. These toxins are used to affect a wide variety of predators belonging to distinct zoological groups and their effect is variable ranging from producing pain to the potential predator’s death. Animals that use toxins for defensive purposes may possess aposematic colorations, which can be used as a baseline for new and interesting ecological approaches in the study of defensive strategies.

This wide variety of toxins that is strongly linked to ecological and biological aspects has worked as a baseline for the obtention of several tools to study different targets in physiological systems and to the propose new directions for the development of drugs or agrochemical products. A good example with arthropod venoms is that many of them are rich in toxins that act on ion channels and other receptors modifying their functions. As these channels and receptors are involved in various physiological functions in different organisms, they become preferential targets for active molecules, usually present in these venoms.  On the other hand, they are frequently, implicated in diseases and are targets of potent drugs. In this sense, animal toxins have helped, as tools, in the knowledge of such targets and have also served as models for drugs to control diseases related to them.

Considering the enormous potential of molecules in the venoms/secretions of the various species of arthropods, this is a promising field to continue to be explored. The thematic series “Arthropods: venoms and biology” aims to bring together contributions on the biological relationships of animals, involving their feeding, venoms and interaction with prey and predators, as well as the mode of action and the pharmacological potential of their toxins, seeking to increase the knowledge of this intricate eco-pharmacological network.

The proposed deadline for submissions is November 30, 2020*. The editors invite you to share your knowledge on this exciting subject and submit your manuscript for consideration.
(*Due to the coronavirus pandemic, JVATiTD  has extended the deadline for submissions to January 31, 2021)

Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. During submission, please indicate clearly in the covering letter that the manuscript is to be considered for the “Arthropods: venoms and biology” series.

If you would like to enquire about the suitability of a manuscript for consideration, please email a pre-submission enquiry to editorial.jvatitd@unesp.br.

Review  |   Anti-inflammatory activities of arthropod peptides: a systematic review

Ariane Teixeira dos Santos1, Gabriela Silva Cruz1, Gandhi Rádis Baptista1,2

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Review  |   Analgesic effects of Phα1β toxin: a review of mechanisms of action involving pain pathways

Juliana Figueira da Silva1, Nancy Scardua Binda1, Elizete Maria Rita Pereira2, Mário Sérgio Lima de Lavor3, Luciene Bruno Vieira4, Alessandra Hubner de Souza2, Flávia Karine Rigo5, Hèlia Tenza Ferrer6, Célio José de Castro Júnior2, Juliano Ferreira7, Marcus Vinicius Gomez2,6

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Review  |   Brazilian Theraphosidae: a toxicological point of view

Keven Wender Rodrigues Macedo1, Lucas Jeferson de Lima Costa1, Jéssica Oliveira de Souza1, Isadora Alves de Vasconcelos1, Jessica Schneider de Castro1, Carlos José Correia de Santana1,2, Ana Carolina Martins Magalhães1, Mariana de Souza Castro1,2, Osmindo Rodrigues Pires Júnior1

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Review  |   Amazonian scorpions and scorpionism: integrating toxinological, clinical, and phylogenetic data to combat a human health crisis in the world’s most diverse rainfores

Adolfo Borges1,2, Matthew R. Graham3, Denise M. Cândido4, Pedro P. O. Pardal5

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Research  |   Novel neuroprotective peptides in the venom of the solitary scoliid wasp Scolia decorata ventralis

Carlos Alberto-Silva1, Fernanda Calheta Vieira Portaro2, Roberto Tadashi Kodama2, Halyne Queiroz Pantaleão1, Marisa Rangel2, Ken-ichi Nihei3, Katsuhiro Konno4

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Research  |   Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibitory activities in vitro

Simon Miguel M. Lopez1,4, Jeremey S. Aguilar1, Jerene Bashia B. Fernandez1, Angelic Gayle J. Lao1, Mitzi Rain R. Estrella1, Mark Kevin P. Devanadera1,2,3, Cydee Marie V. Ramones4, Aaron Joseph L. Villaraza4, Leonardo A. Guevarra Jr.1,2, Myla R. Santiago-Bautista1,2,3, Librado A. Santiago1,2,3

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Review  |   Brown spider venom toxins: what are the functions of astacins, serine proteases, hyaluronidases, allergens, TCTP, serpins and knottins?

Luiza Helena Gremski1, Fernando Hitomi Matsubara1, Hanna Câmara da Justa1, Zelinda Schemczssen-Graeff1, Antonielle Beatriz Baldissera1, Pedro Henrique de Caires Schluga1, Isabel de Oliveira Leite1, Marianna Boia-Ferreira1, Ana Carolina Martins Wille2, Andrea Senff-Ribeiro1, Silvio Sanches Veiga1

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Research  |   Isobolographic analysis reveals antinociceptive synergism between Phα1β recombinant toxin and morphine in a model of cancer pain in C57BL/6J mice

Caio Tavares Aoki1, Rodrigo Andrade Moura1, Luana Assis Ferreira1, Mariana Garcia Mendes1, Duana Carvalho Santos1, Marcio Junior Rezende1, Marcus Vinícius Gomez1, Célio José Castro-Junior1

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Review  |   Armed stem to stinger: a review of the ecological roles of scorpion weapons

Yuri Simone1, Arie van der Meijden1

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Review  |   Scorpion species of medical importance in the Brazilian Amazon: a review to identify knowledge gaps

Jonas Gama Martins1, Gabrielle Cristina Santos2, Rudi Emerson de Lima Procópio3, Eliane Candiani Arantes2, Karla de Castro Figueiredo Bordon2

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Review  |   Widow spiders in the New World: a review on Latrodectus Walckenaer, 1805 (Theridiidae) and latrodectism in the Americas

Marjolly Brigido Caruso1, Pedro Santana Sales Lauria2, Claudio Maurício Vieira de Souza3, Luciana Lyra Casais-e-Silva4, Russolina Benedeta Zingali1

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Research  |   Identification and recombinant expression of an antimicrobial peptide (cecropin B-like) from soybean pest Anticarsia gemmatalis

Luís Felipe Costa Ramos1, João Henrique de Oliveira Rangel1, Guilherme Caldas Andrade1, Carolina Lixa1, Livia Vieira Araujo de Castilho1,2, Fábio César Sousa Nogueira1, Anderson S. Pinheiro1, Fabio Mendonça Gomes3, Cristiane Dinis AnoBom1, Rodrigo Volcan Almeida1, Danielle Maria Perpétua de Oliveira1

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Review  |   The coevolution between telson morphology and venom glands in scorpions (Arachnida)

Wilson R. Lourenço1

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Research  |   Intravitreal injection of peptides PnPa11 and PnPa13, derivatives of Phoneutria nigriventer spider venom, prevents retinal damage

Lays Fernanda Nunes Dourado1, Flavia Rodrigues da Silva1,2, Cibele Rodrigues Toledo1, Carolina Nunes da Silva1, Cleildo Pereira Santana1, Bruna Lopes da Costa1, Maria Elena de Lima3, Armando da Silva Cunha Junior1

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